The Activity of Single Cells in the Midbrain and Hypothalamus of the Cat during Affective Defense Behavior
Results Page 8


Title/summary page

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Introduction
Page 1

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Methods
Pages 2 - 3 - 4

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Results
Pages 5 - 6 - 7 - 8 - 9

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Discussion
Pages 10 - 11

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References
Page 12

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Added figures
Pages 13 - 14 - 15

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Figures
Figures 1 - 2 - 3 - 4 - 5 - 6 - 7 - 8 - 9 - 10

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Tables
Tables 1 - 2 - 3a - 3b - 4 - 5


4. Other cells facilitated during various manipulations.

A majority of the cells recorded from the midbrain, along with a number of cells recorded in the hypothalamus and thalamus, were facilitated during a variety of control manipulations with no common element clearly apparent. Many of these cells had the characteristics of the classical reticular formation cell: little or no tonic firing rate and rapid firing in response to a variety of modalities of sensory stimulation.

5. Cells primarily inhibited during various manipulations.

About one-third of the cells recorded from the hypothalamus, along with several cells from the midline thalamus, were inhibited in firing rate during various manipulations of the cat. In many cases, such as those illustrated in Fig. 10, the cell stopped firing altogether during the manipulation of the cat and did not begin to fire again until several seconds after the manipulation had ceased. The depression of firing rate was not usually specific to anyone particular manipulation although certain manipulations such as affective defense, lifting and dropping and opening of the cage were usually more effective than others such as flashes and clicks. Cells with this response pattern were found throughout the hypothalamic regions explored, but were particularly common in the ventromedial nucleus where two-thirds of the cells were primarily inhibited.

It should be noted that no cell recorded from the midbrain was exclusively inhibited, although several cells decreased in rate during one manipulation and increased during others. Also, no cells were encountered in the study which were inhibited more during affective defense than by any control manipulation of the cat.

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